Complainants own crpc 161 stmts contradictory to fir stmts

Can complainants own CrPC 161 statements, given as part of Chargesheet be contradictory in terms of material information, from what was given at the time of FIR lodging? If this material contradiction is very evident in complainants own statements, to the extent that it changes complete crime scene for the alleged offence, would that be enough ground for discharge under CrPC 239? would it make enough ground for quashing of chargesheet under CrPC 482? Anybody having information on this pls respond. Would also appreciate if somebody can provide relevant judgments.